Numbers of single-chromatid breaks (SCBs) and double sister-chromatid breaks (DSCBs) induced by UV in G1-synchronized cells.
1Sectored colonies resulting from a crossover on the left arm of chromosome V were examined by microarrays. Based on the LOH patterns in the sectors, events were classified as a SCB (usually diagnosed by a 3:1 conversion associated with the crossover) or a DSCB event (usually diagnosed by a 4:0 or 3:1/4:0 hybrid event). Crossovers without detectable gene conversion events were excluded from classification as SCB or DSCB.
2Unselected events are LOH events other than those on the left arm of chromosome V. These events were detected using whole-genome SNP arrays.
3These data are a sub-set of those described previously (Yin and Petes, 2013).
4p<0.0001 compared to wild-type cells treated at 15 J/m2.
Numbers of single-chromatid breaks (SCBs) and double sister-chromatid breaks (DSCBs) induced by UV in G1-synchronized cells.
