Table_2.xls (9.5 kB)
In vitro antiproliferative activity (IC50, μM) against three human tumor cell lines.
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posted on 2013-08-01, 03:07 authored by Dong-Dong Li, Ya-Juan Qin, Jian Sun, Jing-Ran Li, Fei Fang, Qian-Ru Du, Yong Qian, Hai-Bin Gong, Hai-Liang Zhua
Antiproliferative activity was measured using the WST-1 assay. Values are the average of two independent experiments run in triplicate. Variation was generally 5%.
bCancer cells kindly supplied by State Key Laboratory of Pharmaceutical. Biotechnology, Nanjing University; A549 (carcinomic human alveolar basal epithelial cell), MCF-7 (breast cancer, with Her2/neu protein overexpression) and A431 (overexpression of EGFR).
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BiochemistryBiochemistry simulationsBiomacromolecule-ligand interactionsdrug discoverybiophysicsBiophysics simulationsbiotechnologyComputational biologyBiochemical simulationsBiophysic al simulationsMolecular cell biologySignal transductionMembrane receptor signalingmedicinal chemistryDrugs and devicesDrug research and developmentoncologyBasic cancer researchCancer treatmentantiproliferative
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