Genomic variations in prn variants of Austrian B. pertussis samples (n = 77) collected from 2002–2008. Frequencies are given as numbers and as percentage of successfully typed samples (in brackets).
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posted on 2015-07-16, 03:05 authored by Birgit Wagner, Helen Melzer, Georg Freymüller, Sabine Stumvoll, Pamela Rendi-Wagner, Maria Paulke-Korinek, Andreas Repa, Frits R. Mooi, Herwig Kollaritsch, Helmut Mittermayer, Harald H. Kessler, Gerold Stanek, Ralf Steinborn, Michael Duchêne, Ursula Wiedermann1To distinguish the prn variants Prn1 and Prn7, the sequence of the second polymorphic region is needed as well.
Genomic variations in prn variants of Austrian B. pertussis samples (n = 77) collected from 2002–2008. Frequencies are given as numbers and as percentage of successfully typed samples (in brackets).
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Bordetella pertussis Infectionspertussis strainspertussis toxin subunitsaddress polymorphismspertussis casesyears 2002PCR amplificationgenetic variationsequence polymorphismspolymorphic regionsherd immunitySanger sequencingvaccination strategyBordetella pertussismutation systemimmunised hostsvaccine coveragednavaccination coveragepertussis toxinPrn 3Waning immunityvirulence sensor proteinptxP promoter regionvaccine strain TohamaAustrian citiesMLVA analysisptxP 3 alleleNasopharyngeal swabsGenes encodingfimbrial adhesinbvgS polymorphisms
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