Fig 1.tif (4.34 MB)
Establishment of CIN in rats and renal protective effect of EGCG on CIN.
dataset
posted on 2016-02-11, 12:56 authored by Zhao Gao, Yu Han, Yunhui Hu, Xiaoyan Wu, Yongbin Wang, Xiaoqun Zhang, Jinjuan Fu, Xue Zou, Jun Zhang, Xiongwen Chen, Pedro A. Jose, Xi Lu, Chunyu ZengThe rats sequentially received an intravenous infusion of indomethacin, L-NAME, and iopromide to establish CIN. Serum Cr (A) and BUN (B) concentrations were measured 24h, 48h, and 72h after the intravenous injections. Varying dosages of EGCG (5, 10, 20mg/kg body wt) were administered intravenously 15min before the establishment of CIN. Serum Cr (C), BUN (D) and CrCL (E) were measured 24h after the establishment of CIN. (n = 5, * P<0.05 vs. vehicle; # P<0.05 vs. CM).
