Comorbidities and respiratory medications in the total COPD cohort (at study start) further split by the MRC dyspnoea grade (first recorded from study start).

Percentages are based on row total. Comorbidities were searched for any time in the history before the observation period start; respiratory medications were searched for 12 months prior to study start. MRC scoring 1–5 equals to mMRC grades 0–4 with MRC 1 equals to mMRC 0.

a≥4 treatments per year.

Abbreviations: COPD, chronic obstructive pulmonary disease; ICS, inhaled corticosteroids; LABA, long-acting beta-blockers; LAMA, long-acting anticholinergics; MI, myocardial infarction; MRC, Medical Research Council; SABD, short-acting bronchodilators; SD, standard deviation.