Cell surface expression of BCMA, TACI, BR3 and comparative sensitivity of various cancer cell lines to BLyS-gel.
dataset
posted on 2012-10-09, 00:52 authored by Troy A. Luster, Ipsita Mukherjee, Jeffrey A. Carrell, Yun Hee Cho, Jeffrey Gill, Lizbeth Kelly, Andy Garcia, Christopher Ward, Luke Oh, Stephen J. Ullrich, Thi-Sau Migone, Robin Humphreys*
Values determined by flow cytometry and presented as (MFI 1° Ab+MFI 2°Ab) – (MFI 2° Ab only)
**sensitivity determined by incubation with 500 pM BLyS-gel for 72 hrs. Cell viability determined as described in Materials and Methods. Viability reduced by >20% = +; >40% = ++; >60% = +++; >80% = ++++
(?) cell line possibly mis-characterized
Abbreviations: MFI, mean fluorescense intensity; MCL, mantle cell lymphoma; DLBCL; diffuse large B cell lymphoma; BL, Burkitt's lymphoma; MM, multiple myeloma; BCP-ALL, B cell precursor-acute lymphoblastic leukemia; B-CLL, B cell chronic lymphocytic leukemia; ND, not determined
