Candidate domain-fusion templates for structure modeling of a SpaK/SpaR complex.

1

The domains from the structure models of SpaK and SpaR were compared with all structures from PDB. Listed are those domain-fusion templates for which at least one domain from each of SpaK and SpaR had structure similarity LGA_S> = 35%.

2

The residue ranges in modeled SpaK domains are: SpaK_d1: 219–300 and SpaK_d2: 301–459, and the residue ranges in modeled SpaR domains are: SpaR_d1: 1–117 and SpaR_d2: 118–220.

3

N1 denotes a number of residues in the structural domain-fusion template.

4

N2 denotes the number of residues in the corresponding domain from SpaK or SpaR.

5

N denotes the number of superimposed C-alpha atoms that fit under a distance of 5.0 Angstroms.

6

RMSD is the root mean square deviation of N corresponding C-alpha atom pairs from the calculated structural alignment.

7

Seq_ID denotes the sequence identity in % between the domain-fusion template and the corresponding SpaK or SpaR domain calculated from the structural alignment.

8

LGA_S is a measure of the level of structure similarity [20] identified between the domain-fusion template and the corresponding domain from SpaK or SpaR.

Domains from the structural models of SpaK and SpaR were compared with all structures from PDB. Listed are the domain-fusion templates that for at least one domain from the SpaK or SpaR model had a level of structure similarity LGA_S above 37%. LGA_S scores are reported for alignments between each modeled domain of SpaK or SpaR and a domain-fusion template domain. The residue ranges in modeled SpaK domains were: SpaK_d1: 219–300 and SpaK_d2: 301–459, and the residue ranges in modeled SpaR domains were: SpaR_d1: 1–117 and SpaR_d2: 118–220.