Accuracy (weighted area under the ROC curves) of FibroTest, SteatoTest, ActiTest and ALT for the diagnosis of fibrosis, steatosis and NASH adjacent stages/grades in 494 patients with morbid obesity.
dataset
posted on 2012-03-14, 02:11 authored by Thierry Poynard, Guillaume Lassailly, Emmanuel Diaz, Karine Clement, Robert Caïazzo, Joan Tordjman, Mona Munteanu, Hugo Perazzo, Bernard Demol, Robert Callafe, François Pattou, Frederic Charlotte, Pierre Bedossa, Philippe Mathurin, Vlad RatziuNote that the overall Obuchowski measure is not equivalent to an usual area under the ROC curve as weighted according to the distance between stages/grades.
The overall mean (SE) accuracy of FibroTest (Obuchowski measure) was not significantly greater than that of ALT, Z = −0.3 P = 0.77.
The overall accuracy of SteatoTest was significantly greater than that of ALT, Z = 5.2 P<0.0001.
The overall mean accuracy of Actitest (Obuchowski measure) was significantly greater than that of ALT, Z = 4.6 P<0.0001.
