The 10 most up- and downregulated differentially expressed genes in samples udder cleft dermatitis (UCD) lesions in comparison to healthy udder skin tissue.
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posted on 2023-07-24, 17:22 authored by A. S. Vermeersch, M. Ali, Y. Gansemans, F. Van Nieuwerburgh, P. Geldhof, R. Ducatelle, D. Deforce, J. Callens, G. OpsomerThe 10 most up- and downregulated differentially expressed genes in samples udder cleft dermatitis (UCD) lesions in comparison to healthy udder skin tissue.
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transcriptomic changes occurringresults point towardsgene expression patternsgene expression levelsdefective wound repaircytokine receptor interactionskin barrier integritypredominantly inflammatory pathwaysimpaired skin barrierdysregulated inflammatory responseprincipal component analysisdownregulated genes includeddiv >< pinflammatory pathways associatedhealthy udder skin17 signaling pathwaynatural ucd lesionshighest upregulated ones>), 5 (<pathogenesis healthy skinpathway analysisinflammatory moleculesucd lesionsones codinggenes codingchemokine signalingassociated molecules8 (<slpi cxcl8 cxcl5 cxcl2 ccl11 adam12 technology providedsignificantly upregulatedrna seqmultifunctional moleculeskey elementsfriesian cowsdeeper insightclear distinction
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