Subtractive filtering of proteins from Gardenerella vaginalis in the current investigation.

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posted on 2025-03-12, 17:37 authored by Rabbia Riaz, Kanwal Khan, Saltanat Aghayeva, Reaz Uddin

Subtractive filtering of proteins from Gardenerella vaginalis in the current investigation.

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targeted therapeutic strategies network topology assessment maintaining economic feasibility fulfilled specific criteria extensive literature review effective therapeutic options developing new treatments potential drug targets proposed drug target promising drug target drug target identification treating infections related treating infections caused subsequent structural analysis study suggests repurposing proteomic data aimed network topology analyses frequently identified bacterium combatting antibiotic resistance managing bacterial vaginosis gardnerella vaginalis identify virulence factors identify potential compounds could effectively target antibiotic resistance vaginalis bacterial vaginosis identify proteins silico bacterial survival drug targeting virtual screening urgent need systematic comparison selected based screened compounds potentially offering posing challenges multiple antibiotics including subtractive human proteins genetic sequences experimental studies existing drugs encompassing modeling efficient pathway drugbank database db00727 —biological function around 9 approximately 95 approved compounds approach facilitated 000 fda

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