pone.0257911.s003.xlsx (69.61 kB)
Results of CGA-LMM analysis for trimethoprim, methotrexate, rifampin, BRD-4592 in first hypomorph library.
dataset
posted on 2021-10-01, 17:26 authored by Esha Dutta, Michael A. DeJesus, Nadine Ruecker, Anisha Zaveri, Eun-Ik Koh, Christopher M. Sassetti, Dirk Schnappinger, Thomas R. Ioerger(XLSX)
History
Usage metrics
Categories
Keywords
linear mixed modelsgiven inhibitor ).div >< prelevant interacting genesfunctionally interacting genesimproved statistical methodsingle drug concentrationdependence pimproved detectionessential genesbacterial genesyield falseusing hightuberculosis tubercular activitythroughput sequencingslope coefficientsquantify changesprotein depletionpotentially revealingnegative slopesinhibitory compoundsinhibitory compoundindividual mutantsincreasing concentrationshypomorphic strainsexploiting concentrationdual stressesconsidered significantantibiotic exposure
Licence
Exports
RefWorksRefWorks
BibTeXBibTeX
Ref. managerRef. manager
EndnoteEndnote
DataCiteDataCite
NLMNLM
DCDC