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Genomic locations and characteristics of FLEXIs detected in human cell lines, UHRR, and human plasma.

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posted on 2024-09-26, 17:47 authored by Jun Yao, Hengyi Xu, Elizabeth A. Ferrick-Kiddie, Ryan M. Nottingham, Douglas C. Wu, Manuel Ares Jr, Alan M. Lambowitz

Genomic locations and characteristics of FLEXIs detected in human cell lines, UHRR, and human plasma.

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    PLOS Genetics

    Categories

    • Biophysics
    • Biochemistry
    • Microbiology
    • Cell Biology
    • Genetics
    • Molecular Biology
    • Environmental Sciences not elsewhere classified
    • Biological Sciences not elsewhere classified
    • Developmental Biology
    • Hematology

    Keywords

    suggesting overarching mechanismsspecific expression patternsproximate alternative splicingindicating functional interactionsfunctionally related genescoordinately regulating expressionchromatin remodeling proteinalternative splicing factorsfindings identify flexiscellular growth regulatorsdiv >< pincluded splicing factorshuman cell linescytoplasmic functions (<binding sites withinbiomarkers including 53 rbpscytoplasmic functionsbinding sitestranscription factorsincluded rbpsencoding flexisbased biomarkersg e biological functionscellular rnasstructured fullregion correspondingpublic cliplong intronsgene regulationcomprehensive roadmapbinding proteins>., larp4

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