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Functional ontology enrichment of differentially expressed proteins in adult Ae. aegypti permethrin-resistant strain.
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posted on 2023-09-18, 17:31 authored by Abubakar Shettima, Intan Haslina Ishak, Benjamin Lau, Hadura Abu Hasan, Noorizan Miswan, Nurulhasanah OthmanFunctional ontology enrichment of differentially expressed proteins in adult Ae. aegypti permethrin-resistant strain.
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using quantitative proteomicstubulin β chainsup > 8722significantly enriched pathwaysquantitative proteomics analysisquantification via labelfunctional ontology enrichmentfree quantitative proteomicsenolase phosphatase e1downregulated proteins associateddifferentially expressed proteinsdependent atpase β274 downregulated proteins105 downregulated proteins16 sup0 x 10potential protein marker60s ribosomal proteintest selected proteinsl temephos usingdiv >< padult mosquitoes exposed0 statistical softwarebioassay showed resistancepredict insecticide resistancestring softwarebioassay methodaegypti ae insecticide resistanceprotein interactionsprotein identificationprotein extractspb proteincontaining protein≥ 2widespread usetest revealedstudent ’penang islandoxidative phosphorylationmassive databasemajor causelfq ).highlighted upregulatedh15 domainglucosidase 2βgene expressionfold changecitrate cyclecarbon metabolismamino acids25 mg13 upregulated