Table 3.xls (5.5 kB)
Compounds enhancing tritryp trypanothione synthetase (TryS) activity.
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posted on 2016-04-12, 23:01 authored by Diego Benítez, Andrea Medeiros, Lucía Fiestas, Esteban A. Panozzo-Zenere, Franziska Maiwald, Kyriakos C. Prousis, Marina Roussaki, Theodora Calogeropoulou, Anastasia Detsi, Timo Jaeger, Jonas Šarlauskas, Lucíja Peterlin Mašič, Conrad Kunick, Guillermo R. Labadie, Leopold Flohé, Marcelo A. CominiCompounds enhancing tritryp trypanothione synthetase (TryS) activity.
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broad-range TryS inhibitorsscreeningcompounddrug target candidatetrypanothioneinfective Trypanosoma bruceiNovel Chemical Scaffolds Inhibiting Trypanothione SynthetaseMOLnovel chemical entitiesSeveral novel chemical scaffoldsEC 50tri-tryp TryS inhibitorsLeishmania infantum promastigotesPathogenic Trypanosomatids Backgroundthiol-dependent redox metabolismtrypanosomatid
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