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Download fileCandidate regions of chronic kidney disease from Bayesian analysis.
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posted on 2023-01-24, 18:35 authored by Frode Lingaas, Katarina Tengvall, Johan Høgset Jansen, Lena Pelander, Maria H. Hurst, Theo Meuwissen, Åsa Karlsson, Jennifer R. S. Meadows, Elisabeth Sundström, Stein Istre Thoresen, Ellen Frøysadal Arnet, Ole Albert Guttersrud, Marcin Kierczak, Marjo K. Hytönen, Hannes Lohi, Åke Hedhammar, Kerstin Lindblad-Toh, Chao WangCandidate regions of chronic kidney disease from Bayesian analysis.
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wide association analysiskidney cell linesfollowing comparative analysisanova test showedtotal four variantsthree intronic variantshuman regulatory datahuman kidney developmentckd phenotypic variation21 ckd regionsdiv >< pchronic kidney disease117 canine cases2 risk allelescanine ckd206 variantsprotective allelescases carriedhuman populationckd regiontop markerssignificantly higherreln </one variantmay enlightenmagi2 </intergenic regiongalnt18 </fgfr2 </also commonaffects 10
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