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A Retinal heatmap, myopia progression, occlVopen*time interaction.

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posted on 2024-07-19, 17:30 authored by Richard A. Stone, John W. Tobias, Wenjie Wei, Xia Carlstedt, Lixin Zhang, P. Michael Iuvone, Debora L. Nickla

Heatmap of the log2 fold-changes in retina are shown across the sampling times for the occluded vs. open eye differences interacting with time (occlVopen*time interaction) during myopia progression. Key in upper right gives the magnitude of log2 fold-changes. The color indicates the direction of occluded vs. open eye gene expression differences–red, expression higher in occluded eye; blue, expression lower in the occluded eye. See Fig 2 and Tables 4 and S4A. lfc; log2 fold-change, preceded by the ZT of the tissue sampling time. Left ordinate: dendrogram relating the gene clusters. Right ordinate: gene name. B. Choroidal heatmap, myopia progression, occlVopen*time interaction. Heatmap of the log2 fold-changes in retina are shown across the sampling times for the occluded vs. open eye differences interacting with time (occlVopen*time interaction) during myopia progression. Key in upper right gives the magnitude of log2 fold-changes. The color indicates the direction of occluded vs. open eye gene expression differences–red, expression higher in occluded eye; blue, expression lower in the occluded eye. See Fig 2, Tables 4 and S4B. lfc; log2 fold-change, preceded by the ZT of the tissue sampling time. Left ordinate: dendrogram relating the gene clusters. Right ordinate: gene name.

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