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dhfr triple mutant He changes over time (50R/108N).

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posted on 2013-03-16, 09:59 authored by Sean M. Griffing, Giselle M. Rachid Viana, Tonya Mixson-Hayden, Sankar Sridaran, Mohammad Tauqeer Alam, Alexandre Macedo de Oliveira, John W. Barnwell, Ananias A. Escalante, Marinete Marins Povoa, Venkatachalam Udhayakumar

The figure shows variation in He surrounding dhfr for parasites carrying a 51I/108N double mutant during the 1980s (n = 10) and the 1990s (n = 8). The two flat, dashed lines represent two different estimates of neutral He in Brazil.

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