Whole-genome loss of heterozygosity (LOH) events in adrenocortical tumors.

A) Genome-wide distribution of LOH events in each adrenocortical tumor according to the hidden markov model (Partek GS). ACA=adenoma (n=24, total number of LOH=23). ACC=carcinoma (n=22, total number of LOH=2439).

B) Genome-wide distribution of copy neutral LOH identified by merged analysis between copy number alteration and LOH analysis.