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Whole-genome loss of heterozygosity (LOH) events in adrenocortical tumors.

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posted on 2013-09-16, 01:59 authored by Cristina L. Ronchi, Silviu Sbiera, Ellen Leich, Katharina Henzel, Andreas Rosenwald, Bruno Allolio, Martin Fassnacht

A) Genome-wide distribution of LOH events in each adrenocortical tumor according to the hidden markov model (Partek GS). ACA=adenoma (n=24, total number of LOH=23). ACC=carcinoma (n=22, total number of LOH=2439).

B) Genome-wide distribution of copy neutral LOH identified by merged analysis between copy number alteration and LOH analysis.

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