Figure_5.tif (417.41 kB)
Western blot analysis of p53 and the CDK inhibitor p27Kip1 proteins.
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posted on 2013-06-14, 00:34 authored by Birgit Lohberger, Beate Rinner, Nicole Stuendl, Heike Kaltenegger, Bibiane Steinecker-Frohnwieser, Eva Bernhart, Ehsan Bonyadi Rad, Annelie Martina Weinberg, Andreas Leithner, Rudolf Bauer, Nadine KretschmerTotal protein analysis confirmed no significant changes in the p53 expression after costunolide or dehydrocostus lactone treatment. In dehydrocostus lactone treated TE-671 and SW-872 cells, the expression of the CDK inhibitor p27Kip1 was reduced. β-actin was used as loading control. Data shown are representative from at least three independent experiments.
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Biochemistrydrug discoverybiotechnologyMolecular cell biologyCell deathcell divisionCell growthcytometryPlant sciencemedicinal chemistryDrugs and devicesDrug research and developmentpharmacokineticsoncologyBasic cancer researchmetastasisCancer treatmentChemotherapy and drug treatmentComplementary and alternative medicineCancers and neoplasmsBone and soft tissue sarcomasOncology agentsblotp53cdkinhibitor
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