Wavelength-specific effects of intermediate-term irradiation on GAGs, HA, and CS.

Normal human volunteers were treated with sham, UVA, UVA1, PUVA, SSR, and UVB on different sections of their backs 5 times weekly for 4 weeks. ImagePro 3 analysis of treatment-specific effects were evaluated for (a) total GAG content with Hale stain, (b) HA, and (c) CS. Open bars represent epidermal stain intensity, solid bars represent dermal stain intensity, and hatched bars represent stain intensity in the basal layer of the epidermis. (***p<.001, **p<.01, *p<.05, n = 5 for Figure 4a, n = 4 for Figures 4b-c).