WT and TLR4−/− mice treated with streptozotocin display a similar profile of hyperglycemia (A) and changes in body weight (B) over a 24 week period including week 6 (WT n = 12; TLR4−/− n = 9), week 12 (WT n = 10; TLR4−/− n = 13), week 24 (WT n = 12; TLR4−/− n = 12) for diabetes groups and non-diabetes controls were 5 mice per group.

The data are present as the means ± SD.