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Vitamin usage and estrogen supplementation are associated with increased vitamin D levels.

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posted on 2014-04-11, 03:26 authored by Lauren L. Ritterhouse, Rufei Lu, Hemangi B. Shah, Julie M. Robertson, Dustin A. Fife, Holden T. Maecker, Hongwu Du, Charles G. Fathman, Eliza F. Chakravarty, R. Hal Scofield, Diane L. Kamen, Joel M. Guthridge, Judith A. James

(A) Percentage of individuals that reported taking vitamins or not taking vitamins with 25(OH)D levels <20 ng/mL or >20 ng/mL. ****p<0.0001, Fisher's exact test. (B) Levels of 25(OH)D observed in individuals with self-reported vitamin use (n = 46) or no vitamin use (n = 728). Median 25(OH)D levels with interquartile range is shown. ***p<0.001, Mann Whitney test; p<0.05, Shapiro-Wilk and D'Agostino normality test. (C) Percentage of European-American female study participants that reported estrogen supplementation. *p<0.05, Fisher's exact test. (D) Levels of 25(OH)D in European-American female study participants with self-reported estrogen supplementation (n = 63) or no estrogen supplementation (n = 474). Median vitamin D levels with interquartile range are shown. **p<0.01, Mann Whitney test; p<0.05, Shapiro-Wilk and D'Agostino normality test.