Vaccination with Fc-CETP6 reduces inflammation related gene and fibrosis related gene expression profile (experiment 2).
(A) Representative liver sections stained with Masson's trichrome stain and immunohistochemistry stained for α–SMA, a marker of activated stellate cells and myofibroblasts. α–SMA positive cells were expressed near the fibrotic septa (magnification, upper panel x100 and lower panel x100). Three sections from right lobe liver of each rabbit (control group n = 7; Fc-CETP6 group n = 8) were analyzed and ten random fields (magnification, x200) of each section photographed under a microscope (Olympus, BX60). (B) Expression of fibrosis related genes in control rabbits (black bars) and Fc-CETP6 rabbits (white bars) *p<0.05; **p<0.01compared to the control.