Unique high-resolution derivative plots for 6 low-risk HPV genotypes.

Clinical isolates that did not have derivative plots typical of those in our HRM database were analyzed. The HPV42, 62, 70, CP8304, CP8061 and MM8 genotypes were found to display their unique high-resolution derivative plots. The derivative plots were plotted together to reveal the differences among different HPV genotypes (panel A). The derivative plots for two to three measurements of each HPV genotypes were plotted to reveal the minimal inter-assay variability (panel B). Note the consistent derivative plot pattern for each virus subtype.