Type-specificity of -matrix plots.

Statistics and P-values of distributions of for 4-mers in the four type-representative chromosomes. The “rev”, “comp”, and “inv” sets of 's are the terms for conjugate-pairs (,) contributing to , , , and , respectively (Eq. (1)). The numbers of r, c, and i-conjugate pairs of 4-mers are 120, 128, and 120, respectively. The “whole” set consists of 1000 randomly selected pairs from a total of 8484, where in each pair both 4-mers belong to the same -set (Methods) but are otherwise unrelated. In “lead” and “lag”, pairs are -conjugates from the lead-strand and lag-strand, respectively.