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TrkB expression induces cell spreading dispersal.

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posted on 2014-06-24, 03:20 authored by Rudolf Götz, Michael Sendtner

A. Morphology of A549 cell colonies and cell dispersal harbouring empty vector (e vector), or expressing wild-type TrkB (wt) or kinase-dead TrkB (kd) plated on noncoated, collagen I or fibronectin-coated dishes. Phase contrast pictures were taken using a 10x objective. Bar, 200 µm B. Bar graphs show quantification of colonies on non-coated dishes. Bars, mean ± SEM (n = 6). C. Bar graphs show quantification of colonies on collagen I-coated dishes. Bars, mean ± SEM (n = 6); (***, p<0.0002).

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