Trehalose diminished cell motility in PAN-treated human podocytes.

Podocyte were treated with PAN (30 µg/ml) or/and Trehalose (50 mM) for 12 h. (A) PAN-increased podocyte motility was suppressed by trehalose. The representative images were taken under inverted microscope (50×). (B) The number of cells migrating into the gap was calculated for evaluating podocyte motility. The migrated podocytes after PAN treatment increased significantly, whereas trehalose suppressed this enhanced motility. **p<0.01, ***p<0.001 versus CON, n = 6.