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Transient inhibition of Mapk3/1 reduces transcription and translation of transcription factor Egr1.

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posted on 2015-03-24, 04:57 authored by Dayananda Siddappa, Élaine Beaulieu, Nicolas Gévry, Philippe P. Roux, Vilceu Bordignon, Raj Duggavathi

A) Treatment of immature mice with single dose of 25μg/g of PD0325901 inhibited the expression of hCG-induced expression of Egr1 1h and 4h hCG. B) Abundance of Egr1 protein in granulosa cells of the inhibitor and vehicle treated mice. Actb was used as loading control.

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