Time-response analysis showing percentage changes in <sup>1</sup>H-NMR-detected metabolite levels following treatment of SF188 pediatric glioblastoma cells with PI-103 (5×GI<sub>50</sub>).

<p>Data are expressed as percentage of treated to control (% T/C) and presented as the mean ± SD, n≥3.</p><p>Two-tailed unpaired <i>t</i> test was used to compare results in treated cells to controls.</p><p>*P<0.05,</p><p>**P<0.005,</p><p>***P<0.0005.</p>