The intracellular calcium chelator BAPTA decreased cell retention of I-HIV at 20 uM (panel A) and increased transport rate of I-HIV at 10 uM (panel B).
2013-02-20T03:30:50Z (GMT) by
This is consistent with an increased rate of transport across the BMEC. The calcium channel blocker verapamil had no affect on transport. The calcium ionophore A23187 increased I-HIV permeability (panel C) and decreased TEER (panel D) in BMEC.