The effect of cytokine treatment and inhibition of TG2 activity on the adhesion capacity of astrocytes onto Fn.

A) Adhesion of rat astrocytes onto Fn coated wells after treatment with cytokines and subsequent inhibition of TG2 activity. B) TG activity after treatment with cytokines and subsequent inhibition of TG2 activity. C) Cell viability measured using the propidium iodide assay. Data are expressed as mean+s.e.m., n = 15 (A) or n = 5 per condition (B,C), #P<0.001 versus vehicle-treated control cells and *P<0.05, **P<0.01, ***P<0.001 versus vehicle-treated control or matched cytokine-treated cells.