The effect of HIV related proteins on hippocampal inflammation was measured in adolescent WT and HIV-1 tg rats.

A) Analysis of hippocampal gene expression of inflammatory markers showed increased expression of the potent chemokine, Mcp-1, in non-drug treated HIV-1 tg rats compared to WT controls (*p<0.05). B) In contrast, once daily meloxicam administration attenuated Mcp-1 expression in HIV-1 tg rats, normalizing inflammatory gene expression to WT levels (p>0.05). Data are presented as mean ± SEM.