Figure_7.tif (6.01 MB)
The cnot8m1061 mutation affects FGF receptor expression levels.
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posted on 2014-12-05, 03:24 authored by Peter Koch, Heiko B. Löhr, Wolfgang DrieverThe expression of the four zebrafish FGF receptor genes fgfr1, 2, 3 and 4 was analyzed by WISH in cnot8m1061 mutants and WT siblings at 1, 2 and 3 dpf. All pictures show lateral views. Embryos were genotyped by PCR. Scale bar 100 µm in A for A–X.
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dopaminergic neuron developmentCnot 8 activity differentiallymRNA decay pathwaycaudalcnot 8m mutantsfgf 3 genem 1061 mutationCnot 8 deadenylase componentcontrol genesCnot 8 activity resultsdopaminergic differentiationdisplays deadenylase activitymRNA levelshybridization signal levelsbulk mRNA turnoverm 1061 causesFgf 3Affects Expression LevelsFGF target genes
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