The cadmium binding site.

(A) The cadmium binding site located between 2 neighboring molecules in the crystal. The cadmium ion is shown as a green sphere. The Grb2 SH2 molecule is shown in thick lines, whereas a symmetrically-related molecule is shown in thin lines. Green dashed lines indicated the coordinate and hydrogen bonds. (B) The corresponding site in Grb2 SH2/AICD (PDB ID: 3MXC). The red sphere represents a water molecule.

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