Figure_4.tif (446.75 kB)
The R6H-CXCL8 mutant activated CXCR1 in neutrophils.
figure
posted on 2011-12-09, 01:11 authored by Jose Sarmiento, Christie Shumate, Katsutoshi Suetomi, Aishwarya Ravindran, León Villegas, Krishna Rajarathnam, Javier NavarroHuman neutrophils loaded with Indo-1 were treated with and without 1 µM of the CXCR2 inhibitor SB225002 and stimulated with 100 nM of CXCL8 (A and D), the CXCR2 agonist CXCL1 (B and E) and the R6H-CXCL8 mutant (C and F). The record is representative of at least five independent experiments.
