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The GRAIP approach.

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posted on 2013-02-21, 10:32 authored by Jeremy L. Peirce, Karl W. Broman, Lu Lu, Elissa J. Chesler, Guomin Zhou, David C. Airey, Amanda E. Birmingham, Robert W. Williams

This cartoon summarizes the GRAIP approach. First (1) parental happlotypes are regenerated if they are not already known and (2) the parents are permuted. Next (3) the population of offspring is regenerated using the permuted genotypes and (4) permuted maps are generated using the non-permuted phenotypes. Finally, (5) the significance of the permuted maps are compared at a pointwise and whole genome basis with the original map.

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    graip

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