The FtsY from Pyrococcus furiosus.

(A) Sequence alignment of FtsY/SRs of known structure including Pfu, Thermus aquaticus (Taq), Thermotoga maritima (Tma), Mycoplasma mycoides (Mmyc) and Arabidopsis thaliana (Atha) (chloroplast). The protease sensitive sites observed in E.coli and Taq FtsYs upon FtsY•Ffh complex formation are indicated (x). The ELEX2LX3D in the N domain is indicated. (B) Overall structure of the apo monomer of Pfu-FtsY. Two views related by a 180° rotation along a vertical axis are shown. The secondary structure elements of Pfu-FtsY are indicated. α-helices and conserved motifs of the SRP/SR-GTPases subfamily are labeled.

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