TLR4 linkage disequilibrium (LD) plot.

This plot was generated by Haploview program using data from this study. Five common (frequency≥0.05) htSNPs formed one block. The SNP name, e.g., SNP1, SNP2, etc., indicated five htSNPs genotyped in this study. Four common haplotypes were identified. The level of pairwise r2, which indicated the association degree between two SNPs in the LD block, was shown in the cell of the LD structure in numeric. The level of pair-wise D', which indicated the strength of LD between two SNPs, was shown in the LD structure in gray scale.