Systemic inflammatory response in TNF-R−/− and WT mice after DSS.

(A) Spleen was isolated and weighed at day 8 after colitis induction. The percentage of granulocytes (Gr-1+) (B) or monocytes (F4/80+) (C) in the spleens were examined by flow cytometry. Representative plots were shown. Data represent the mean±SD of four to six mice per group from three independent experiments. *P<0.05 vs WT control mice; #P<0.05, ##P<0.01 vs WT mice after DSS.

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