Systemic inflammatory response in TNF-R−/− and WT mice after DSS.
(A) Spleen was isolated and weighed at day 8 after colitis induction. The percentage of granulocytes (Gr-1+) (B) or monocytes (F4/80+) (C) in the spleens were examined by flow cytometry. Representative plots were shown. Data represent the mean±SD of four to six mice per group from three independent experiments. *P<0.05 vs WT control mice; #P<0.05, ##P<0.01 vs WT mice after DSS.