Figure_3.tif (6.21 MB)
Spontaneous development of marked inflammation in the colon of Shp2 CKO mice.
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posted on 2014-03-27, 03:51 authored by Hironori Yamashita, Takenori Kotani, Jung-ha Park, Yoji Murata, Hideki Okazawa, Hiroshi Ohnishi, Yonson Ku, Takashi MatozakiA: Hematoxylin-eosin staining of paraffin-embedded sections of the cecum, mid-colon, and rectum from control or Shp2 CKO mice at 3 weeks of age. Arrowheads and the asterisk indicate inflammatory infiltrates and a crypt abscess, respectively. B: Hematoxylin-eosin staining of the ileum from control and Shp2 CKO mice at 3 weeks of age. Arrowheads and the arrow indicate inflammatory infiltrates and abnormal villus structure, respectively. All data are representative of three separate experiments. Scale bars, 100 μm.
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anatomybiological tissueepitheliumEpithelial cellscell biologyCell processesCell growthSignal transductioncell signalingSignaling cascadesTyrosine kinase signaling cascadeCell movement signalingRas signalingCellular typesMolecular cell biologyGastroenterology and hepatologyInflammatory bowel diseaseModel organismsAnimal modelsMouse modelsmarkedinflammationcolonshp2cko
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