Sorted mature lung macrophages (MHCII int, CD11C+, CD11B+) and alveolar macrophages (MHCII int, CD11C+, CD11B−) obtained from naïve lungs or lungs after LPAL were studied after 18 h in culture.

Supernatants evaluated for MIP-2α showed spontaneous release only in mature lung macrophages (* indicates p<0.0001, n = 12 lungs).