Sliding window correlation (SWC) to identify GO terms associated with serum neutralization titers.

(A) Immunologically important GO terms correlated with log10(PRNT80) listed by time window with associated p-value indicated significance of correlation. (B) Correlated GO terms plotted as log10(PRNT80) vs Normalized GO term DBGGA Bayesian z-scores. The GO term Viral life cycle had a negative correlation with seroconversion at the windowed time points –6, –5, and –4 pSN (upper panel), while Positive regulation of T cell cytokine production shows a positive correlation with seroconversion at the windowed time points –4, –3, and –2 pSN (lower panel).