Six weeks of pressure overload induced hypertrophy and lung remodeling despite preserved systolic function.

(A): Left ventricular mass index (LVMI), (B): heart weight-to-body weight ratio (HW/BW), (C): endocardial fractional shortening (eFS) and (D): lung weight-to-body weight ratio (LW/BW) of control and pressure overloaded rats at 2, 4 and 6 weeks after aortic banding (AoB). Data are mean ±SEM. Significantly different vs. age-matched control: *, vs. AoB at 2 weeks: §, vs. AoB at 4 weeks: #. The numbers in the bars indicate group size.