Single nucleotide polymorphisms detected in M. bovis BCG spontaneous mutants resistant to IP compounds.

Wild-type alleles are denoted by a ‘−’ character. Where mixtures of alleles were seen in the population this is indicated, e.g. A/V demonstrates both the genotype coding for alanine and the genotype coding for valine is seen.

a

Genomic positions are relative to M. bovis BCG str. Pasteur 1173P2 chromosome (Genbank accession: NC_008769.1).