Serotype distribution in Malaysia.

(A) National data 2000–2012 [3], [12]. (B) 2012 data (to 12 July 2012) by state* via the Sentinel Surveillance System [12]. *One patient in Sarawak was infected with DENV-1 (not shown on graph). National data (A) demonstrated that the dominant DENV serotypes circulating in the country changed continually throughout the period of 2000 to 2011. DENV-4 was less prevalent than the other three serotypes and constituted <20% of the serotypes for all years. Regional data from 1 January 2012 to 12 July 2012 reported via the Sentinel Surveillance System (B) showed a heterogeneous distribution of DENV serotypes in the separate states. DENV, dengue virus.