Figure_4.tif (1.7 MB)
SPM results for the voxel-wise correlation between changes in metabolism and changes in self-reports of cocaine craving (Neutral - Cocaine-cues) for the Placebo and the Methylphenidate conditions (p<0.005 uncorrected, cluster size >200 voxels).
figure
posted on 2010-07-09, 00:23 authored by Nora D. Volkow, Gene-Jack Wang, Dardo Tomasi, Frank Telang, Joanna S. Fowler, Kith Pradhan, Millard Jayne, Jean Logan, Rita Z. Goldstein, Nelly Alia-Klein, Christopher WongFor Placebo the correlations were negative (decreases in metabolism associated with increases in craving) whereas with Methylphenidate these were positive (increases in metabolism associated with increases in craving).