SCANS longitudinal imaging cohort.

All available DTI scans without EPI warping were used in our analyses. Exit event coding: Death = patient passed away; Dementia = patient developed a primary dementia syndrome; Heart implant = patient was unable to do further MR sessions due to a heart implant; ICH = subject met exclusion criteria after intracerebral haemorrhage; Cognition only = patient withdrew from MR sessions but remained in study for cognition; Withdrawal = patient formally withdrew from the study; Loss to follow-up = patient was lost to follow-up; Major stroke = patient met exclusion criteria after major ischaemic stroke; Cardiac arrest = major cognitive impairment related to hypoxia was seen in a patient after a cardiac arrest.