Fig_4.tif (424.42 kB)
Role of the endothelium in response to Br-OA.
figure
posted on 2016-01-28, 12:39 authored by Hlengiwe P. Madlala, Thomas Metzinger, Fanie R. van Heerden, Cephas T. Musabayane, Kanigula Mubagwa, Chantal DessyConcentration-response curves for solvent and Br-OA in mesenteric arteries (A) and aortic rings (B) isolated from Wistar rats pre-contracted with PE (5 μM). Curves were obtained in endothelium-denuded and intact arteries. Some endothelium-intact vessels were incubated in the presence of INDO (10 μM) only or in combination with L-NoArg (100 μM) prior to addition of the drug. Values shown are means ± SEM (n = 7). * p ˂ 0.001 vs control, # vs intact endothelium.
