Fig_6.tif (1.89 MB)
Residues involved in binding mapped onto HEPN crystal structure.
figure
posted on 2015-09-14, 02:46 authored by Xinlu Li, Marie Ménade, Guennadi Kozlov, Zheping Hu, Zheng Dai, Peter S. McPherson, Bernard Brais, Kalle GehringResidues that produced chemical shift changes during the NMR titrations with DMSO (A), AN670 (B), AK968 (C) and AN652 (D) were mapped onto the HEPN crystal structure. In each structure, DMSO-binding residues are labeled in blue and additional residues binding to the hit candidates are labeled in red.
