Regulation of matrix metalloproteinases and its inhibitors in the aorta of AngII-infused rats: Restoration by statins.

A. Gene expression of MMP-9 and TIMP-1 was evaluated by real time PCR and data are expressed as mean±SEM of 10 animals per group, *p<0.05 vs control; # p<0.05 vs AngII. B. Evaluation of matrix balance by the ratio MMP-9 vs TIMP-1. Values higher or lower than 1 reflect degradation or accumulation, respectively, of matrix proteins.